Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | REN | P00797 | 10/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598190 | 0.83 | REN (0.35) | GPR119RENCYP3A4 | |
| SCHEMBL4597030 | 0.79 | ESR2 (0.40) | GPR119 | |
| SCHEMBL4598116 | 0.77 | NR1H2 (0.42) | GPR119 | |
| SCHEMBL4598172 | 0.77 | REN (0.39) | GPR119RENCYP3A4HTR2A | |
| SCHEMBL13490819 | 0.72 | USP30 (0.41) | GPR119 | |
| SCHEMBL5941459 | 0.72 | GPR119 (0.42) | GPR119RENCYP3A4HTR2A | |
| SCHEMBL5942072 | 0.72 | GPR119 (0.42) | GPR119RENCYP3A4 | |
| SCHEMBL5942374 | 0.72 | REN (0.47) | GPR119RENCYP3A4 | |
| SCHEMBL8263840 | 0.71 | JAK2 (0.42) | GPR119 | |
| SCHEMBL8264180 | 0.71 | JAK2 (0.43) | GPR119REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908471-A1 | Tetrahydropyridines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |