SCHEMBL4598235

SCHEMBL4598235

Oc1cc[c]c2ccc3ccccc3c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.44
CYP1A2 P05177 2/20 0.42
POLB P06746 1/20 0.41
HSD17B10 Q99714 4/20 0.40
USP2 O75604 1/20 0.40
PAK1 Q13153 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 3/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ERN1 O75460 1/20 0.38
HPRT1 P00492 1/20 0.37
HPGD P15428 2/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18317256 0.78 ALDH1A1 (0.47) CYP1A2HSD17B10ALDH1A1TSHRTDP1
SCHEMBL5030608 0.76 PTPN22 (0.47) PTPN22CYP1A2POLBHSD17B10USP2
SCHEMBL9957632 0.75 ALDH1A1 (0.39) CYP1A2HSD17B10ALDH1A1TSHRTDP1
SCHEMBL845365 0.73 ALDH1A1 (0.42) PTPN22CYP1A2HSD17B10ALDH1A1TSHR
SCHEMBL4599438 0.73 HPGD (0.41) PTPN22CYP1A2POLBHSD17B10ALDH1A1
SCHEMBL9172751 0.73 MMP2 (0.49) ALDH1A1TSHRTDP1KDM4EMAPT
SCHEMBL144610 0.72 HSD17B10 (0.46) PTPN22CYP1A2POLBHSD17B10ALDH1A1
SCHEMBL1899901 0.72 ALDH1A1 (0.61) CYP1A2HSD17B10ALDH1A1TSHRTDP1
SCHEMBL28549567 0.71 GPR55 (0.41)
SCHEMBL50091 0.71 IDO1 (0.48) PTPN22CYP1A2POLBHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483582-B1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2008-04-16 EP claimed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP claimed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO claimed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US claimed
EP-2841943-B1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES KEMIRA OYJ (FI) 2023-09-27 EP disclosed
US-20160258936-A1 METHOD FOR ANALYZING GAS SAMPLES TURUN YLIOPISTO (FI) 2016-09-08 US disclosed
WO-2015059363-A1 METHOD FOR ANALYZING GAS SAMPLES TURUN YLIOPISTO (FI) 2015-04-30 WO disclosed
US-20150094234-A1 Method for characterizing and/or determining samples AQSENS OY (FI) 2015-04-02 US disclosed
EP-2841943-A1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES Aqsens Oy (FI) 2015-03-04 EP disclosed
WO-2013160547-A1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES HAERMAE HARRI (FI) 2013-10-31 WO disclosed
US-7381567-B2 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2008-06-03 US disclosed
EP-1483582-B1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2008-04-16 EP disclosed
US-7211440-B2 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2007-05-01 US disclosed
US-20070015284-A1 Dissociative fluorescence enhancement assay HEMMILA ILKKA 2007-01-18 US disclosed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP disclosed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO disclosed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US disclosed