SCHEMBL4599438

SCHEMBL4599438

Oc1cccc2ccc3[c]cccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP1A2 P05177 3/20 0.41
TSHR P16473 3/20 0.41
MAPT P10636 3/20 0.41
THRB P10828 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
APP P05067 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
SNCA P37840 1/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 6/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
DNMT1 P26358 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
MCL1 Q07820 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL845365 0.79 ALDH1A1 (0.42) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL18317416 0.79 ALDH1A1 (0.46) HPGDHSD17B10CYP1A2TSHRTHRB
SCHEMBL386939 0.77 HSD17B10 (0.44) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL5031513 0.75 ALDH1A1 (0.38) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL15271216 0.75 ALDH1A1 (0.34) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL18317387 0.75 CDK4 (0.40) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL380657 0.74 CYP1A2 (0.65) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL4598235 0.73 PTPN22 (0.44) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL25108 0.72 ALDH1A1 (0.55) HPGDHSD17B10CYP1A2TSHRMAPT
SCHEMBL16107752 0.72 CYP1A2 (0.56) HPGDHSD17B10CYP1A2TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483582-B1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2008-04-16 EP claimed
US-7345172-B2 Methods and compositions for detecting polynucleotide duplex damage and errors CALFORNIA INSTITUTE OF TECHNOLOGY (US) 2008-03-18 US claimed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP claimed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO claimed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US claimed
EP-2841943-B1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES KEMIRA OYJ (FI) 2023-09-27 EP disclosed
US-20160258936-A1 METHOD FOR ANALYZING GAS SAMPLES TURUN YLIOPISTO (FI) 2016-09-08 US disclosed
WO-2015059363-A1 METHOD FOR ANALYZING GAS SAMPLES TURUN YLIOPISTO (FI) 2015-04-30 WO disclosed
US-20150094234-A1 Method for characterizing and/or determining samples AQSENS OY (FI) 2015-04-02 US disclosed
EP-2841943-A1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES Aqsens Oy (FI) 2015-03-04 EP disclosed
WO-2013160547-A1 METHOD FOR CHARACTERIZING AND/OR DETERMINING SAMPLES HAERMAE HARRI (FI) 2013-10-31 WO disclosed
US-7381567-B2 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2008-06-03 US disclosed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP disclosed
US-6808884-B2 INTERCALATION COMPOUND FOR USE IN THE DIAGNOSIS AND DETECTION OF GENETIC DISORDERS CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-10-26 US disclosed
WO-2002057492-A9 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INST OF TECHN (US) 2003-12-18 WO disclosed
EP-1349962-A1 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-10-08 EP disclosed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO disclosed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US disclosed
US-20020155470-A1 Methods and compositions for detecting polynucleotide duplex damage and errors CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-24 US disclosed
WO-2002057492-A1 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155470-A1 Methods and compositions for detecting polynucleotide duplex damage and errors POLRMT, POLN, POLM HPGD 2904/4885HSD17B10 2144/4885CYP1A2 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.