SCHEMBL4598484

SCHEMBL4598484

O=C(Cl)c1cc(S(=O)(=O)Cl)cc(S(=O)(=O)Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890395 0.95 LCK (0.41) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL5278000 0.87 TPMT (0.40) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL11886838 0.86 TPMT (0.39) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL2003193 0.86 CES2 (0.40) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL15870330 0.81 FLT1 (0.31) ALDH1A1TSHR
SCHEMBL11668400 0.81 LCK (0.58) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL8747785 0.81 LCK (0.58) ALDH1A1HSD17B10TDP1LCKFYN
SCHEMBL2568764 0.79 LMNA (0.40) ALDH1A1HSD17B10LCKFYN
SCHEMBL218559 0.79 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1
SCHEMBL30525020 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108069853-B Synthetic method of 3, 5-dichlorobenzoyl chloride 江西吉翔医药化工有限公司 2020-12-22 CN disclosed
EP-2858740-B1 METHOD FOR MAKING MEMBRANE COMPOSITE POLYAMIDE MEMBRANE WITH COMBINATION OF DIFFERENT POLYFUNCTIONAL AMINE-REACTIVE MONOMERS DDP SPECIALITY ELECTRONIC MAT US INC (US) 2020-03-25 EP disclosed
US-9925500-B2 Membrane derived from polyfunctional amine and combination of different polyfunctional amine-reactive monomers DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-27 US disclosed
US-9630149-B2 Composite polyamide membrane with improved structure DOW GLOBAL TECHNOLOGIES LLC (US) 2017-04-25 US disclosed
US-9610542-B2 Composite polyamide membrane with increased carboxylic acid functionality DOW GLOBAL TECHNOLOGIES LLC (US) 2017-04-04 US disclosed
CN-106349121-A Preparation method of 3,5-dichlorobenzoyl chloride 上海绿麟达新材料科技有限公司 2017-01-25 CN disclosed
US-20150174534-A1 MEMBRANE DERIVED FROM POLYFUNCTIONAL AMINE AND COMBINATION OF DIFFERENT POLYFUNCTIONAL AMINE-REACTIVE MONOMERS DOW GLOBAL TECHNOLOGIES LLC 2015-06-25 US disclosed
US-20150165387-A1 COMPOSITE POLYAMIDE MEMBRANE WITH IMPROVED STRUCTURE THE DOW CHEMICAL COMPANY 2015-06-18 US disclosed
EP-2874733-A1 COMPOSITE POLYAMIDE MEMBRANE WITH INCREASED CARBOXYLIC ACID FUNCTIONALITY Dow Global Technologies LLC (US) 2015-05-27 EP disclosed
US-20150129485-A1 COMPOSITE POLYAMIDE MEMBRANE WITH INCREASED CARBOXYLIC ACID FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-14 US disclosed
US-7456195-B2 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-25 US disclosed
EP-1910298-A2 PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS Brystol-Myers Squibb Company (US) 2008-04-16 EP disclosed
WO-2007002313-A2 PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-01-04 WO disclosed
US-20070003539-A1 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants BRISTOL-MYERS SQUIBB COMPANY (US) 2007-01-04 US disclosed
WO-2001010838-A1 MULTIVALENT COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2001-02-15 WO disclosed
EP-0144810-B1 CURABLE COMPOSITION PPG INDUSTRIES, INC. (US) 1989-08-23 EP disclosed
EP-0144810-A2 Curable composition PPG INDUSTRIES, INC. (US) 1985-06-19 EP disclosed
EP-0142805-A2 Aminoplast curable compositions containing disulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1985-05-29 EP disclosed
US-4501854-A FILMS, COATINGS, PAINTS, MOLDINGS, LAMINATES PPG INDUSTRIES, INC. (US) 1985-02-26 US disclosed
US-4500680-A BENZENESULFONIC ACIDS PPG INDUSTRIES, INC. (US) 1985-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070003539-A1 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants F12, F11, F7 ALDH1A1 2963/4885HSD17B10 4277/4885TDP1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.