Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156912 | 0.75 | NR1H4 (0.31) | TSHRALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL4608770 | 0.75 | ALDH1A1 (0.33) | PTGDR2PTGDRALDH1A1NR1H2KDM4E | |
| SCHEMBL391724 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1ALOX15HTTMAPK1 | |
| SCHEMBL5442350 | 0.73 | JAK2 (0.38) | ALDH1A1UCHL1USP30OPRK1KDM4E | |
| SCHEMBL5442593 | 0.72 | CDK5 (0.36) | ALDH1A1MAPK8NR1H2KDM4EPOLB | |
| SCHEMBL2157499 | 0.69 | KDM4E (0.34) | PTGDR2PTGDRTSHRALDH1A1HSD17B10 | |
| SCHEMBL3098417 | 0.68 | ALDH1A1 (0.37) | ALDH1A1ALOX15HSD17B10KDM4ECYP3A4 | |
| SCHEMBL4610689 | 0.67 | FPR2 (0.38) | ALDH1A1MTNR1AMTNR1BNR1H2KDM4E | |
| SCHEMBL14277672 | 0.67 | ALDH1A1 (0.39) | TSHRALDH1A1ALOX15HTTMAPK1 | |
| SCHEMBL5447286 | 0.67 | POLB (0.36) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910337-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2006138744-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060293320-A1 | Heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293320-A1 | Heteroaryl derivatives for treating viruses | HAVCR2, MAVS, EIF2AK2 | PTGDR2 4654/4885PTGDR 4482/4885TSHR 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.