Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610689 | 0.76 | FPR2 (0.38) | ALDH1A1KDM4ELMNANR1H2HDAC6 | |
| SCHEMBL4598798 | 0.75 | PTGDR2 (0.35) | ALDH1A1KDM4ECYP3A4CYP2C19NR1H2 | |
| SCHEMBL25219534 | 0.73 | NR1H2 (0.41) | ALDH1A1KDM4ENR1H2PDE4BMAPT | |
| SCHEMBL5447286 | 0.70 | POLB (0.36) | RXFP1MAPTCCKBR | |
| SCHEMBL15724297 | 0.68 | KDM4E (0.33) | ALDH1A1KDM4EHPGDCYP2C19HDAC6 | |
| SCHEMBL4610205 | 0.68 | GAA (0.39) | ALDH1A1KDM4ELMNANR1H2HDAC6 | |
| SCHEMBL2156616 | 0.68 | PTGDR (0.35) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL21427098 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHDAC6SMN1; SMN2 | |
| SCHEMBL2156912 | 0.66 | NR1H4 (0.31) | ALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL14487422 | 0.66 | HDAC6 (0.37) | PDE4BHDAC6CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910337-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2006138744-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060293320-A1 | Heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293320-A1 | Heteroaryl derivatives for treating viruses | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 2522/4885NPSR1 4023/4885KDM4E 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.