SCHEMBL328794

SCHEMBL328794

Brc1cc(C(Br)Br)c(Br)c(Br)c1Br

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
APEX1 P27695 1/20 0.36
AKR1B1 P15121 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
EIF2AK2 P19525 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455527 0.83 TDP1 (0.40) TDP1APEX1AKR1B1CA1CA2
SCHEMBL11522162 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL4453850 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL4601560 0.79 TDP1 (0.37) TDP1APEX1AKR1B1CA1CA2
SCHEMBL2882117 0.79 TDP1 (0.37) TDP1APEX1CA2CA4
SCHEMBL5186322 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL9373547 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL28651893 0.77 MAPT (0.43) TDP1APEX1AKR1B1
SCHEMBL4599386 0.77 TDP1 (0.41) TDP1APEX1AKR1B1
SCHEMBL10455644 0.76 GABRA1 (0.41) TDP1APEX1AKR1B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024635-B Method for preparing pentabromobenzyl polyacrylate 潍坊裕凯化工有限公司 2024-04-02 CN claimed
CN-117024635-A Method for preparing pentabromobenzyl polyacrylate 潍坊裕凯化工有限公司 2023-11-10 CN claimed
CN-115850958-A Flame-retardant polyamide elastomer material and preparation method and application thereof 沧州旭阳化工有限公司 2023-03-28 CN claimed
CN-109836817-B Halogen flame retardant and application thereof 杭州本松新材料技术股份有限公司 2022-02-25 CN claimed
CN-113321862-A Plastic blended ultraviolet-resistant flame-retardant optical cable and preparation method thereof 黄锦鹏 2021-08-31 CN claimed
CN-112206457-A Biomass gel-based dry water powder extinguishing agent and preparation method thereof 武汉理工大学 2021-01-12 CN claimed
EP-2617472-B1 FERROCENE-BASED FIRE EXTINGUISHING COMPOSITION XIAN WESTPEACE FIRE TECH CO LTD (CN) 2020-06-24 EP claimed
EP-3166989-B1 PREPARATION OF BROMINE-CONTAINING POLYMERS USEFUL AS FLAME RETARDANTS BROMINE COMPOUNDS LTD (IL) 2020-03-25 EP claimed
EP-3166980-B1 PREPARATION OF BROMINE-CONTAINING POLYMERS AND THEIR APPLICATION AS FLAME RETARDANTS BROMINE COMPOUNDS LTD (IL) 2020-03-18 EP claimed
CN-109957222-A A kind of low precipitation flame retardant PBT composition 杭州本松新材料技术股份有限公司 2019-07-02 CN claimed
WO-2006008738-A1 SYNTHESIS OF AROMATIC POLYHALOGENATED HALOMETHYL COMPOUNDS BROMINE COMPOUNDS LTD. (IL) 2006-01-26 WO claimed
WO-2006006154-A2 NOVEL FIRE RETARDANTS BROMINE COMPOUNDS LTD. (IL) 2006-01-19 WO claimed
US-20050124746-A1 Pentabromobenzyl alkyl ethers and their use as fire retardants BROMINE COMPOUNDS LTD. (IL) 2005-06-09 US claimed
CN-1625540-A Pentabromobenzyl alkyl ethers and their use as fire retardants BROMINE COMPOUNDS LTD (IL) 2005-06-08 CN claimed
EP-1470097-A1 PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS Bromine Compounds Ltd. (IL) 2004-10-27 EP claimed
WO-2003064361-A1 PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS BROMINE COMPOUNDS LTD. (IL) 2003-08-07 WO claimed
US-6028156-A Process for the preparation of poly-(halobenzyl acrylate) BROMINE COMPOUNDS, LTD. (IL) 2000-02-22 US claimed
EP-0390042-B1 Process for the preparation of bromosubstituted aromatic esters of alfa,beta unsaturated acids BROMINE COMPOUNDS LTD (IL) 1994-01-19 EP claimed
US-5072028-A Process for the preparation of bromo-substituted aromatic esters of α,β-unsaturated acids BROMINE COMPOUNDS LIMITED (IL) 1991-12-10 US claimed
EP-0390042-A1 Process for the preparation of bromosubstituted aromatic esters of alfa,beta unsaturated acids Bromine Compounds Ltd. (IL) 1990-10-03 EP claimed