SCHEMBL4455527

SCHEMBL4455527

Brc1cc(C(Br)C(Br)c2cc(Br)c(Br)c(Br)c2Br)c(Br)c(Br)c1Br

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
APEX1 P27695 1/20 0.36
AKR1B1 P15121 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
EIF2AK2 P19525 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2152106 0.85 TDP1 (0.34) TDP1APEX1
SCHEMBL328794 0.83 TDP1 (0.40) TDP1APEX1AKR1B1CA1CA2
SCHEMBL11522162 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL9373547 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL2882117 0.79 TDP1 (0.37) TDP1APEX1CA2CA4
SCHEMBL4453850 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL5186322 0.79 TDP1 (0.37) TDP1APEX1
SCHEMBL4601560 0.79 TDP1 (0.37) TDP1APEX1AKR1B1CA1CA2
SCHEMBL4599386 0.77 TDP1 (0.41) TDP1APEX1AKR1B1
SCHEMBL11660852 0.76 TDP1 (0.32) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605207-B2 Heat resistance; using with polystyrene fthermoplastic foams BROMINE COMPOUNDS LTD. (IL) 2009-10-20 US disclosed
US-20080281024-A1 Flame Retardant Bromobenzyl Systems BROMINE COMPOUNDS LTD. (IL) 2008-11-13 US disclosed
EP-1951798-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS Bromine Compounds Ltd. (IL) 2008-08-06 EP disclosed
WO-2007057900-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS BROMINE COMPOUNDS LTD. (IL) 2007-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281024-A1 Flame Retardant Bromobenzyl Systems PBRM1, PFAS, BPTF TDP1 542/4885APEX1 3777/4885AKR1B1 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.