SCHEMBL4601560

SCHEMBL4601560

OC(Br)c1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
AKR1B1 P15121 3/20 0.33
APEX1 P27695 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
EIF2AK2 P19525 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455527 0.79 TDP1 (0.40) TDP1AKR1B1APEX1CA1CA2
SCHEMBL328794 0.79 TDP1 (0.40) TDP1AKR1B1APEX1CA1CA2
SCHEMBL2882117 0.75 TDP1 (0.37) TDP1APEX1CA2CA4
SCHEMBL11522162 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL5186322 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL4453850 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL9373547 0.75 TDP1 (0.37) TDP1APEX1
SCHEMBL29634824 0.75 TDP1 (0.33) TDP1AKR1B1CA1CA2CA4
SCHEMBL7149093 0.75 ADRA2A (0.39) TDP1APEX1
SCHEMBL4599386 0.73 TDP1 (0.41) TDP1AKR1B1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820112-B Pentabromoacrylate Process for preparing benzyl esters 江苏欣舟化工科技有限公司 2025-01-24 CN claimed
CN-117820112-A Preparation method of pentabromobenzyl acrylate 江苏欣舟化工科技有限公司 2024-04-05 CN claimed
EP-0047866-B1 ESTERS OF TETRABROMOPHTHALIC ACID, PREPARATION AND USE AS FIRE-PROOFING AGENTS IN PLASTICS Chemische Fabrik Kalk GmbH (DE) 1983-05-18 EP claimed
US-4376837-A Flame retardant tetrabromophthalic acid esters useful in synthetic resins CHEMISCHE FABRIK KALK GMBH (DE) 1983-03-15 US claimed
CN-117820112-B Pentabromoacrylate Process for preparing benzyl esters 江苏欣舟化工科技有限公司 2025-01-24 CN disclosed
CN-117820112-B Pentabromoacrylate Process for preparing benzyl esters 江苏欣舟化工科技有限公司 2025-01-24 CN disclosed
CN-117820112-A Preparation method of pentabromobenzyl acrylate 江苏欣舟化工科技有限公司 2024-04-05 CN disclosed
CN-117820112-A Preparation method of pentabromobenzyl acrylate 江苏欣舟化工科技有限公司 2024-04-05 CN disclosed
EP-2764071-B1 FLAME RETARDANTS, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN POLYURETHANE AND POLYISOCYANURATE FOAMS BROMINE COMPOUNDS LTD (IL) 2016-12-07 EP disclosed
CN-103987811-B Fire retardant, its preparation method and its purposes in polyurethane and polyisocyanurate foam 溴化合物有限公司 2016-08-24 CN disclosed
US-9309377-B2 Flame retardants, processes for their preparation and uses thereof in polyurethane and polyisocyanurate foams BROMINE COMPOUNDS LTD. (IL) 2016-04-12 US disclosed
US-20140303271-A1 FLAME RETARDANTS, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN POLYURETHANE AND POLYISOCYANURATE FOAMS BROMINE COMPOUNDS LTD. (IL) 2014-10-09 US disclosed
EP-0325788-B1 3,3'-oxy-bis([2,2'-di(bromomethyl)]) propanoic acid derivates, processes for their preparation and their use as flame retardant agents BROMINE COMPOUNDS LTD (IL) 1994-03-16 EP disclosed
EP-0305196-B1 Novel trisubstituted symmetrical triazines, their preparation and their use BROMINE COMPOUNDS LTD (IL) 1994-01-19 EP disclosed
US-4977262-A FLAME RETARDANTS FOR PLASTICS BROMINE COMPOUNDS LIMITED (IL) 1990-12-11 US disclosed
US-4898900-A FLAME-RETARDENTS HAVING HIGH BROMINE CONTENTS, IMPROVED THERMAL STABILITY BROMINE COMPOUNDS LTD. (IL) 1990-02-06 US disclosed
EP-0325788-A2 3,3'-oxy-bis([2,2'-di(bromomethyl)]) propanoic acid derivates, processes for their preparation and their use as flame retardant agents Bromine Compounds Ltd. (IL) 1989-08-02 EP disclosed
EP-0305196-A2 Novel trisubstituted symmetrical triazines, their preparation and their use Bromine Compounds Ltd. (IL) 1989-03-01 EP disclosed
US-4376837-A Flame retardant tetrabromophthalic acid esters useful in synthetic resins CHEMISCHE FABRIK KALK GMBH (DE) 1983-03-15 US disclosed
US-4376837-A Flame retardant tetrabromophthalic acid esters useful in synthetic resins CHEMISCHE FABRIK KALK GMBH (DE) 1983-03-15 US disclosed