Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305613 | 0.88 | APP (0.57) | LTA4HNR5A1APPKDM4ERECQL | |
| SCHEMBL842057 | 0.88 | APP (0.57) | LTA4HNR5A1APPKDM4ERECQL | |
| SCHEMBL1478767 | 0.88 | APP (0.57) | LTA4HNR5A1APPKDM4ERECQL | |
| SCHEMBL77538 | 0.85 | LTA4H (0.59) | LTA4HNR5A1APPLMNACYP1A2 | |
| SCHEMBL17072090 | 0.85 | ABL1 (0.50) | LTA4HNR5A1CTNNB1ESR2 | |
| SCHEMBL841097 | 0.83 | NR5A1 (0.62) | LTA4HNR5A1APPLMNAKDM4E | |
| SCHEMBL16305604 | 0.83 | APP (0.53) | LTA4HNR5A1APPESR2KDM4E | |
| SCHEMBL1923910 | 0.83 | LTA4H (0.54) | LTA4HNR5A1APPLMNACYP1A2 | |
| SCHEMBL14595233 | 0.82 | APP (0.46) | APPCTNNB1KDM4ERECQL | |
| SCHEMBL13645868 | 0.82 | DRD2 (0.46) | CTNNB1LMNAKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910263-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | Nicholas Piramal India Limited (IN) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007004091-A2 | NOVEL INTERMEDIATES USEFUL FOR THE PREPARATION OF COENZYMES, PROCESS FOR THE PREPARATION OF NOVEL INTERMEDIATES AND AN IMPROVED PROCESS FOR THE PREPARATION OF COENZYMES | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
| US-5932196-A | DEOXYARBUTIN DERIVATIVES, STORAGE STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |