Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599126 | 0.88 | MEN1 (0.41) | ALDH1A1ENPP3ENPP1ENPP2L3MBTL1 | |
| SCHEMBL4598688 | 0.83 | TDP1 (0.43) | ALDH1A1SMN1; SMN2TDP1FAAHMAOB | |
| SCHEMBL4598731 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TDP1FAAHMAOB | |
| SCHEMBL4598887 | 0.82 | CA12 (0.35) | ALDH1A1FAAHGAAMAPK1CA12 | |
| SCHEMBL4611281 | 0.80 | FAAH (0.40) | ALDH1A1SMN1; SMN2TDP1FAAHMAOB | |
| SCHEMBL4600500 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1MAOBENPP3 | |
| SCHEMBL4599161 | 0.76 | HTT (0.49) | ALDH1A1SMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL4598684 | 0.75 | BCHE (0.43) | ALDH1A1MAOBL3MBTL1GAANPC1 | |
| SCHEMBL4599999 | 0.75 | L3MBTL1 (0.45) | ALDH1A1SMN1; SMN2TDP1ENPP2L3MBTL1 | |
| SCHEMBL4599861 | 0.73 | GAA (0.40) | ALDH1A1ENPP1ENPP2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | disclosed |