SCHEMBL4598887

SCHEMBL4598887

C=CCNc1[c]ccc(OS(C)(=O)=O)c1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
ALDH1A1 P00352 2/20 0.33
FAAH O00519 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 2/20 0.31
HPGD P15428 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB3 P13945 1/20 0.31
CA14 Q9ULX7 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599588 0.82 KDM4E (0.37) CA12CA2ALDH1A1FAAHGAA
SCHEMBL4599126 0.82 MEN1 (0.41) CA12CA1CA2CA9ALDH1A1
SCHEMBL4599760 0.82 ALDH1A1 (0.40) CA12CA1CA2CA9ALDH1A1
SCHEMBL4599912 0.77 ALDH1A1 (0.38) CA12CA2ALDH1A1GAAHPGD
SCHEMBL4599391 0.77 HTT (0.40) CA12CA1CA2CA9ALDH1A1
SCHEMBL4599803 0.74 ALDH1A1 (0.42) CA12CA2ALDH1A1GAAHPGD
SCHEMBL4598684 0.71 BCHE (0.43) ALDH1A1GAAKDM4E
SCHEMBL4600346 0.71 APLNR (0.48) ALDH1A1TSHRMAPK1
SCHEMBL4598425 0.69 HPGD (0.37) CA12CA1CA2CA9ALDH1A1
SCHEMBL4600271 0.69 LMNA (0.42) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP claimed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO claimed
EP-1910320-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2008-04-16 EP disclosed
WO-2007011065-A2 INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-01-25 WO disclosed