Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 3/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | TEK | Q02763 | 3/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5634749 | 0.96 | KDM4E (0.92) | KDM4ELMNAMAPK1NPSR1PLA2G10 | |
| SCHEMBL39557 | 0.86 | LMNA (1.00) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL30120700 | 0.86 | LMNA (1.00) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3079277 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL1760797 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL4353000 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9081231 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3076842 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3074710 | 0.85 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL8877868 | 0.85 | LMNA (0.76) | KDM4ELMNAMAPK1NPSR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979938-B | Preparation method of FAP-alpha inhibitor and intermediate 6-methoxy-4-carboxylic acid quinoline of tumor diagnosis imaging agent | 南京恒远科技开发有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113979938-A | Preparation method of FAP-alpha inhibitor and intermediate 6-methoxy-4-carboxylic acid quinoline of tumor diagnosis imaging agent | 南京恒远科技开发有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-1535272-A | Nitrogen-containing bicyclic heterocycles | ʷ | 2004-10-06 | — | — | CN | claimed |
| CN-113979938-B | Preparation method of FAP-alpha inhibitor and intermediate 6-methoxy-4-carboxylic acid quinoline of tumor diagnosis imaging agent | 南京恒远科技开发有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113979938-A | Preparation method of FAP-alpha inhibitor and intermediate 6-methoxy-4-carboxylic acid quinoline of tumor diagnosis imaging agent | 南京恒远科技开发有限公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |