Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.92 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600323 | 0.96 | KDM4E (1.00) | KDM4ELMNAMAPK1NPSR1PLA2G10 | |
| SCHEMBL30120700 | 0.85 | LMNA (1.00) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL39557 | 0.85 | LMNA (1.00) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9081231 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3079277 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3076842 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL3074710 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL1760797 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL4353000 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 | |
| SCHEMBL29048387 | 0.84 | LMNA (0.97) | KDM4ELMNAMAPK1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135422-A1 | Nitrogen-containing bicycle heterocycles for use as antibacterials | SMITHKLINE BEECHAM P.L.C. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135422-A1 | Nitrogen-containing bicycle heterocycles for use as antibacterials | NRDC, NUCB2, NISCH | KDM4E 4047/4885LMNA 2883/4885MAPK1 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.