SCHEMBL4600340

SCHEMBL4600340

O=C(I)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 9/20 0.79
HPGD P15428 2/20 0.63
MAPT P10636 2/20 0.63
MEN1 O00255 1/20 0.63
CYP2C19 P33261 1/20 0.63
HTT P42858 1/20 0.63
RECQL P46063 1/20 0.63
BLM P54132 1/20 0.63
SMAD3 P84022 1/20 0.63
KMT2A Q03164 1/20 0.63
PRMT1 Q99873 1/20 0.63
ACE2 Q9BYF1 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
DRD1 P21728 3/20 0.50
NAALAD2 Q9Y3Q0 1/20 0.47
TTR P02766 1/20 0.46
MAPK10 P53779 1/20 0.46
MAPK14 Q16539 1/20 0.46
ALOX12 P18054 2/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600492 0.92 FTO (0.67) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL29938908 0.88 FTO (1.00) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL543293 0.88 FTO (1.00) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL25103 0.87 FTO (0.78) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL29406840 0.87 FTO (0.78) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL1694038 0.86 FTO (0.72) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL14213150 0.86 FTO (0.79) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL17970938 0.85 FTO (0.74) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL8567853 0.85 FTO (1.00) FTOHPGDMAPTMEN1CYP2C19
SCHEMBL9428406 0.85 FTO (0.74) FTOHPGDMAPTMEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-1238116-B1 PROCESS FOR LABELING A NUCLEIC ACID BIO MERIEUX (FR) 2008-04-16 EP claimed
EP-1259809-B1 BIOSENSORS, METHOD FOR OBTAINING SAME AND USES THEREOF PASTEUR INSTITUT (FR) 2006-12-13 EP claimed
US-RE38256-E1 Safe slurry photosensitive composition superior in image formation capabilities such as resolution and sensitivity and containing no harmful compound KABUSHIKI KAISHA TOSHIBA (JP) 2003-09-23 US disclosed
EP-0853628-B1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN EV (DE) 2002-10-02 EP disclosed
WO-2002051794-A2 CONNECTABLE BIOCHEMICAL PINCERS AND SYNTHETIC RECEPTORS FOR MOLECULAR ORGANISATION AND MANIPULATION OF BIOMOLECULES TAMPE ROBERT (DE) 2002-07-04 WO disclosed
EP-0853628-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE Forschungsverbund Berlin e.V. (DE) 1998-07-22 EP disclosed
WO-1997005155-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN E.V. (DE) 1997-02-13 WO disclosed