Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601910 | 0.91 | PPARG (0.45) | PPARG | |
| SCHEMBL4601368 | 0.84 | PPARG (0.42) | PPARGLIPECYP3A4CYP2C19 | |
| SCHEMBL4603253 | 0.80 | PPARG (0.47) | PPARGLIPE | |
| SCHEMBL4602114 | 0.80 | PPARG (0.46) | PPARG | |
| SCHEMBL4603015 | 0.78 | PPARG (0.45) | PPARG | |
| SCHEMBL4600570 | 0.74 | PPARG (0.48) | PPARGLIPEBCHEL3MBTL1 | |
| SCHEMBL4601766 | 0.72 | ALDH1A1 (0.51) | PPARG | |
| SCHEMBL4601414 | 0.72 | EGFR (0.44) | PPARGLIPEBCHEL3MBTL1CYP2C9 | |
| SCHEMBL4602508 | 0.71 | PDE4A (0.40) | BCHEL3MBTL1 | |
| SCHEMBL4601430 | 0.68 | SCN9A (0.38) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |