Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712787 | 0.92 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1538365 | 0.92 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3084515 | 0.83 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3084517 | 0.83 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1789211 | 0.82 | GABRR1 (0.32) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL6036625 | 0.81 | THRB (0.38) | THRBTSHRGABRR1GABRR2BLM | |
| SCHEMBL6036567 | 0.81 | THRB (0.38) | THRBTSHRGABRR1GABRR2BLM | |
| SCHEMBL2583139 | 0.79 | GABRR1 (0.33) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL5365860 | 0.78 | LMNA (0.36) | THRBLMNA | |
| SCHEMBL5374505 | 0.78 | LMNA (0.36) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172383-B1 | Method of making fluoropolymers | UNIV NORTH CAROLINA (US) | 2008-04-16 | — | — | EP | claimed |
| US-6289807-B1 | Open, pressureless ink duct having a low surface energy coating to aid in forming a roll of ink | KOENIG & BAUER AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| US-5922833-A | FORMING THE SOLUTION OF FLUOROPOLYMER SUCH AS FLUOROACRYLATE, FLUOROVINYLETHER OR FLUOROSTYRENE AND CARBON DIOXIDE, VENTING CARBON DIOXIDE TO SEPARATE IT FROM FLUOROPOLYMER AND ISOLATING THE POLYMER | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-07-13 | — | — | US | disclosed |