SCHEMBL712787

SCHEMBL712787

O=C(O)C=CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)CC=CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
GABRR1 P24046 2/20 0.42
GABRR2 P28476 2/20 0.42
BLM P54132 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
LMNA P02545 1/20 0.42
APEX1 P27695 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538365 1.00 TSHR (0.42) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL4600709 0.92 THRB (0.40) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL3084515 0.90 TSHR (0.46) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL3084517 0.90 TSHR (0.46) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL2583139 0.87 GABRR1 (0.33) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL1789211 0.85 GABRR1 (0.32) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL14801551 0.80 TSHR (0.46) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL455399 0.80 TSHR (0.46) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL7076723 0.77 GABRR1 (0.35) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL17433692 0.77 PPARA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3509135-B1 COMPOSITE MEMBRANE, ANODE STRUCTURE INCLUDING THE COMPOSITE MEMBRANE, LITHIUM BATTERY INCLUDING THE ANODE STRUCTURE, AND METHOD OF PREPARING THE COMPOSITE MEMBRANE SAMSUNG ELECTRONICS CO LTD (KR) 2022-04-27 EP claimed
EP-2081056-B1 Laminated diffractive optical element and resin composition therefor CANON KK (JP) 2011-01-05 EP claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-11156750-B2 Laminated diffractive optical element and method for manufacturing laminated diffractive optical element CANON KABUSHIKI KAISHA (JP) 2021-10-26 US disclosed
US-20210223437-A1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME CANON KK (JP) 2021-07-22 US disclosed
US-10996375-B2 Optical element and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2021-05-04 US disclosed
EP-3385760-B1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME CANON KK (JP) 2020-11-11 EP disclosed
EP-2482103-B1 Method of manufacturing a diffractive optical element NIKON CORP (JP) 2020-10-28 EP disclosed
US-10577446-B2 Resin precursor composition for optical materials, optical element obtained from the composition, and diffractive optical element configured using the optical element NIKON CORPORATION (JP) 2020-03-03 US disclosed
EP-3187907-B1 RESIN PRECURSOR COMPOSITION FOR OPTICAL MATERIALS, OPTICAL ELEMENT OBTAINED FROM SAID COMPOSITION, AND DIFFRACTIVE OPTICAL ELEMENT CONFIGURED USING SAID OPTICAL ELEMENT NIKON CORP (JP) 2019-09-25 EP disclosed
US-7282525-B2 Pellicle, producing method thereof and adhesive MITSUI CHEMICALS, INC. (JP) 2007-10-16 US disclosed
EP-1830205-A1 CLOSE-BONDED DIFFRACTIVE OPTICAL ELEMENT, OPTICAL MATERIAL USED THEREFOR, RESIN PRECURSOR, AND RESIN PRECURSOR COMPOSITION Nikon Corporation (JP) 2007-09-05 EP disclosed
EP-1830204-A1 CLOSE-BONDED DIFFRACTIVE OPTICAL ELEMENT, OPTICAL MATERIAL USED THEREFOR, RESIN PRECURSOR, AND RESIN PRECURSOR COMPOSITION Nikon Corporation (JP) 2007-09-05 EP disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
US-20020127360-A1 Pellicle, producing method thereof and adhesive MITSUI CHEMICALS, INC. (JP) 2002-09-12 US disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577446-B2 Resin precursor composition for optical materials, optical element obtained from the composition, and diffractive optical element configured using the optical element CAD, RARA, RAD51 TSHR 4637/4885GABRR1 1503/4885GABRR2 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.