Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704095 | 0.80 | NOTUM (0.32) | NOTUM | |
| SCHEMBL4601311 | 0.80 | — | — | |
| SCHEMBL11142330 | 0.79 | NOTUM (0.31) | NOTUM | |
| SCHEMBL11358287 | 0.75 | CYP2D6 (0.36) | TSHRNOTUMCYP2C19 | |
| SCHEMBL6353676 | 0.73 | HPGD (0.33) | HTTALDH1A1MAPT | |
| SCHEMBL6353265 | 0.71 | HPGD (0.33) | — | |
| Acrylic Acid SCHEMBL3135012 | 0.71 | THRB (0.33) | — | |
| SCHEMBL709529 | 0.70 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6361567 | 0.70 | — | — | |
| SCHEMBL9416551 | 0.69 | GSTP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166980-B1 | PREPARATION OF BROMINE-CONTAINING POLYMERS AND THEIR APPLICATION AS FLAME RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2020-03-18 | — | — | EP | disclosed |
| US-20190144754-A1 | PROCESS FOR PREPARING BROMINE- CONTAINING POLYMERS | BROMINE COMPOUNDS LTD. (IL) | 2019-05-16 | — | — | US | disclosed |
| US-10227531-B2 | Preparation of bromine-containing polymers and their application as flame retardants | BROMINE COMPOUNDS LTD. (IL) | 2019-03-12 | — | — | US | disclosed |
| US-9988332-B2 | Preparation of bromine-containing aromatic compounds and their application as flame retardants | BROMINE COMPOUNDS LTD. (IL) | 2018-06-05 | — | — | US | disclosed |
| EP-2941411-B1 | PREPARATION OF BROMINE-CONTAINING AROMATIC COMPOUNDS AND THEIR APPLICATION AS FLAME RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2018-03-21 | — | — | EP | disclosed |
| US-20170145313-A1 | PREPARATION OF BROMINE-CONTAINING POLYMERS AND THEIR APPLICATION AS FLAME RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2017-05-25 | — | — | US | disclosed |
| EP-3166980-A1 | PREPARATION OF BROMINE-CONTAINING POLYMERS AND THEIR APPLICATION AS FLAME RETARDANTS | Bromine Compounds Ltd. (IL) | 2017-05-17 | — | — | EP | disclosed |
| US-20170022133-A1 | PREPARATION OF BROMINE-CONTAINING AROMATIC COMPOUNDS AND THEIR APPLICATION AS FLAME RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2017-01-26 | — | — | US | disclosed |
| EP-2764071-B1 | FLAME RETARDANTS, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN POLYURETHANE AND POLYISOCYANURATE FOAMS | BROMINE COMPOUNDS LTD (IL) | 2016-12-07 | — | — | EP | disclosed |
| US-9481621-B2 | Preparation of bromine-containing aromatic compounds and their application as flame retardants | BROMINE COMPOUNDS LTD. (IL) | 2016-11-01 | — | — | US | disclosed |
| EP-1470097-B1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2008-04-16 | — | — | EP | disclosed |
| US-20070267608-A1 | Novel Fire Retardants | BROMINE COMPOUNDS LTD. (IL) | 2007-11-22 | — | — | US | disclosed |
| CN-1319923-C | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD (IL) | 2007-06-06 | — | — | CN | disclosed |
| EP-1773934-A2 | NOVEL FIRE RETARDANTS | Bromine Compounds Ltd. (IL) | 2007-04-18 | — | — | EP | disclosed |
| US-7091270-B2 | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD. (IL) | 2006-08-15 | — | — | US | disclosed |
| WO-2006006154-A2 | NOVEL FIRE RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2006-01-19 | — | — | WO | disclosed |
| US-20050124746-A1 | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD. (IL) | 2005-06-09 | — | — | US | disclosed |
| CN-1625540-A | Pentabromobenzyl alkyl ethers and their use as fire retardants | BROMINE COMPOUNDS LTD (IL) | 2005-06-08 | — | — | CN | disclosed |
| EP-1470097-A1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | Bromine Compounds Ltd. (IL) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064361-A1 | PENTABROMOBENZYL ALKYL ETHERS AND THEIR USE AS FIRE RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022133-A1 | PREPARATION OF BROMINE-CONTAINING AROMATIC COMPOUNDS AND THEIR APPLICATION AS FLAME RETARDANTS | CBR3, CBR1, AHR | TSHR 785/4885TP53 2760/4885HTT 3557/4885 |
| US-20070267608-A1 | Novel Fire Retardants | COXFA4, NDUFS5, SQOR | TSHR 3009/4885TP53 591/4885HTT 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.