Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964699 | 0.80 | GBA1 (0.50) | ALDH1A1CXCR3SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL966612 | 0.80 | BCL2L1 (0.48) | ALDH1A1CXCR3LMNASMN1; SMN2NPSR1 | |
| SCHEMBL963729 | 0.74 | NPSR1 (0.54) | ALDH1A1HPGDLMNASMN1; SMN2NPSR1 | |
| SCHEMBL4077665 | 0.73 | ALDH1A1 (0.78) | ALDH1A1HPGDPKMLMNASMN1; SMN2 | |
| SCHEMBL20388009 | 0.73 | CXCR3 (0.73) | ALDH1A1CXCR3HPGDLMNASMN1; SMN2 | |
| SCHEMBL963555 | 0.71 | HSD11B1 (0.46) | ALDH1A1LMNASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL20393917 | 0.71 | MAPT (0.66) | ALDH1A1CXCR3HPGDLMNASMN1; SMN2 | |
| SCHEMBL1169642 | 0.70 | CXCR3 (1.00) | ALDH1A1CXCR3HPGDSMN1; SMN2MEN1 | |
| SCHEMBL1874466 | 0.70 | LMNA (0.72) | ALDH1A1HPGDPKMLMNASMN1; SMN2 | |
| SCHEMBL963548 | 0.69 | CA12 (0.47) | LMNAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |