SCHEMBL4600959

SCHEMBL4600959

CCc1cc(CBr)c(CC)cc1CBr

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
TAAR1 Q96RJ0 1/20 0.31
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14069869 1.00 ALOX15 (0.41) ALOX15ALOX12GRIN2DGRIN3BGRIN1
SCHEMBL338590 0.83 TRPA1 (0.32)
SCHEMBL3205225 0.83 GRIN2D (0.50) ALOX15ALOX12GRIN2DGRIN3BGRIN1
Formaldehyde SCHEMBL27723347 0.76 GRIN2D (0.46) ALOX15ALOX12GRIN2DGRIN3BGRIN1
SCHEMBL9172056 0.75 CYP4F2 (0.39) ALOX15ALOX12GRIN2DGRIN3BGRIN1
SCHEMBL1581441 0.75 SMN1; SMN2 (0.40) GABRA1GABRB2POLB
SCHEMBL11556055 0.75 TRPA1 (0.41) GABRA1GABRB2TAAR1
SCHEMBL3374862 0.73 RIPK1 (0.36) ALOX15GABRA1GABRB2HTT
SCHEMBL14785481 0.73 IDO1 (0.39) ALOX15ALOX12TAAR1HTT
SCHEMBL232176 0.71 ALDH1A1 (0.42) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1117277-B1 ORGANIC EL DEVICE TDK CORP (JP) 2008-04-23 EP disclosed
EP-1096835-B1 ORGANIC EL DEVICE TDK CORP (JP) 2008-04-23 EP disclosed
US-6445126-B1 INORGANIC DIELECTRIC APERTURE INJECTION LAYER TDK CORPORATION (JP) 2002-09-03 US disclosed
US-6404126-B1 LAYER COMPRISING ALKALI METAL OXIDE, ALKALINE EARTH METAL OXIDE AND SILICON OXIDE, GERMANIUM OXIDE OR A MIXTURE OF SILICON OXIDE AND GERMANIUM OXIDE AS A THIRD COMPONENT. TDK CORPORATION (JP) 2002-06-11 US disclosed
EP-0672741-B1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2001-10-17 EP disclosed
US-6288487-B1 Organic electroluminescent device with a high-resistance inorganic electron injecting and transporting layer TDK CORPORATION (JP) 2001-09-11 US disclosed
EP-1117277-A1 ORGANIC EL DEVICE TDK Corporation (JP) 2001-07-18 EP disclosed
US-6249085-B1 Organic electroluminescent device with a high-resistance inorganic hole injecting and transporting layer TDK CORPORATION (JP) 2001-06-19 US disclosed
EP-1096835-A1 ORGANIC EL DEVICE TDK Corporation (JP) 2001-05-02 EP disclosed
EP-1061778-A1 ORGANIC EL DEVICE TDK Corporation (JP) 2000-12-20 EP disclosed
EP-1030539-A1 ORGANIC EL DEVICE TDK Corporation (JP) 2000-08-23 EP disclosed
EP-0637621-B1 Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL CO (JP) 2000-05-17 EP disclosed
US-5980781-A HAVING LIGHT EMITTING LAYER BETWEEN THE ELECTRODES CONSISTING OF ONE PAIR OF AN ANODE AND A CATHODE, AT LEAST ONE OF WHICH ELECTRODES IS TRANSPARENT OR SEMI-TRANSPARENT, WHEREIN SAID LIGHT EMITTING LAYER COMPRISES A POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-09 US disclosed
US-5759709-A Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-02 US disclosed
US-5589320-A Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-12-31 US disclosed
US-5543079-A POLYARYLENE VINYLIDENES HAVING THREE DIFFERENT UNITS AND CONTAINING ETHER, SULFIDE OR ESTER GROUPS; SOLBUILITY; HIGH QUANTUM YIELD WITH LOW DRIVE VOLTAGE; ELECTRICAL THIN FILMS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-06 US disclosed
EP-0672741-A1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-09-20 EP disclosed
EP-0637621-A1 Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-08 EP disclosed