SCHEMBL4601309

SCHEMBL4601309

Fc1cc(Br)c(F)c(Br)c1F

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
APEX1 P27695 1/20 0.32
KDM1A O60341 2/20 0.31
KCNH2 Q12809 2/20 0.31
KDM1B Q8NB78 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
AKR1B1 P15121 1/20 0.30
RAPGEF3 O95398 3/20 0.30
RAPGEF4 Q8WZA2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439846 0.84 CA1 (0.38) CA12CA1CA2CA7CA13
SCHEMBL6553501 0.81 CA1 (0.36) CA12CA1CA2CA7CA13
SCHEMBL1043011 0.79 CA12 (0.35) CA12CA1CA2CA7CA13
Ethylene SCHEMBL27505929 0.79 CA1 (0.35) CA12CA1CA2CA7CA13
Bromide SCHEMBL10982440 0.79 CA1 (0.35) CA12CA1CA2CA7CA13
Bromide SCHEMBL10982443 0.79 CA1 (0.35) CA12CA1CA2CA7CA13
SCHEMBL30395917 0.78 ALDH1A1 (0.33) CA12CA1CA2CA7CA13
SCHEMBL11884949 0.77 APEX1 (0.38) CA12CA1CA2CA7CA13
Cyanide SCHEMBL21633856 0.77 CA1 (0.33) CA12CA1CA2CA7CA13
SCHEMBL22769992 0.77 CA12 (0.33) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1913005-B1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2013-07-31 EP disclosed
CN-101263148-B Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXON MOBIL CHEM PATENTS INC 2012-06-06 CN disclosed
CN-101263148-A Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2008-09-10 CN disclosed
EP-1913005-A1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2008-04-23 EP disclosed
US-7297653-B2 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-20 US disclosed
WO-2007018743-A1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2007-02-15 WO disclosed
US-20070021575-A1 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-01-25 US disclosed
US-3772878-A METHOD OF GENERATING POWER DU PONT 1973-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021575-A1 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization ARF4, ARF1, ARFIP2 CA12 4027/4885CA1 4004/4885CA2 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.