Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | DUT | P33316 | 14/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602019 | 0.88 | PPARG (0.45) | PPARGDUTCNR1CNR2 | |
| SCHEMBL4634146 | 0.84 | PPARG (0.46) | PPARGDUTCNR1CNR2 | |
| SCHEMBL4602971 | 0.83 | PPARG (0.41) | PPARGDUT | |
| SCHEMBL4600676 | 0.83 | PPARG (0.44) | PPARGCNR1CNR2 | |
| SCHEMBL4602109 | 0.77 | GPR84 (0.43) | PPARG | |
| SCHEMBL3206932 | 0.76 | PPARG (0.61) | PPARGCNR1CNR2 | |
| SCHEMBL4601014 | 0.76 | GPR84 (0.42) | PPARG | |
| SCHEMBL4602988 | 0.75 | FFAR1 (0.53) | PPARGCNR1CNR2 | |
| SCHEMBL3212943 | 0.75 | CNR2 (0.44) | PPARGCNR1CNR2 | |
| SCHEMBL27737205 | 0.74 | PPARG (0.43) | PPARGCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |