Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DUT | P33316 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634146 | 0.88 | PPARG (0.46) | PPARGMTNR1ACNR1CNR2DUT | |
| SCHEMBL4601397 | 0.88 | PPARG (0.41) | PPARGCNR1CNR2DUT | |
| SCHEMBL4602109 | 0.88 | GPR84 (0.43) | PPARGMEN1HTTKMT2AHPGD | |
| SCHEMBL4600676 | 0.87 | PPARG (0.44) | PPARGMTNR1ACNR1CNR2TDP1 | |
| SCHEMBL4602971 | 0.84 | PPARG (0.41) | PPARGDUTALDH1A1HTTKMT2A | |
| SCHEMBL4601014 | 0.81 | GPR84 (0.42) | PPARGMEN1KMT2A | |
| SCHEMBL4600593 | 0.78 | PPARG (0.43) | PPARGTDP1ALDH1A1MEN1HTT | |
| SCHEMBL4602137 | 0.77 | PPARG (0.41) | PPARGTDP1 | |
| SCHEMBL27737205 | 0.76 | PPARG (0.43) | PPARGSLC6A9MTNR1ACNR1CNR2 | |
| SCHEMBL27716279 | 0.76 | PPARG (0.44) | PPARGMTNR1ACNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |