Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602109 | 0.94 | GPR84 (0.43) | GPR84PPARGMEN1KMT2AROS1 | |
| SCHEMBL4602137 | 0.89 | PPARG (0.41) | GPR84PPARGROS1ALKNPC1 | |
| SCHEMBL4600593 | 0.87 | PPARG (0.43) | GPR84PPARGMEN1KMT2AROS1 | |
| SCHEMBL27716275 | 0.86 | PPARG (0.40) | GPR84PPARGMEN1KMT2AROS1 | |
| SCHEMBL4602019 | 0.81 | PPARG (0.45) | PPARGMEN1KMT2A | |
| SCHEMBL3219692 | 0.78 | RAB9A (0.41) | GPR84NPC1RAB9A | |
| SCHEMBL27716319 | 0.78 | PPARG (0.41) | GPR84PPARGROS1ALKNPC1 | |
| SCHEMBL27716322 | 0.77 | PPARG (0.41) | PPARGMEN1KMT2AROS1ALK | |
| SCHEMBL3202441 | 0.77 | PPARG (0.56) | PPARG | |
| SCHEMBL3204951 | 0.77 | FFAR1 (0.54) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |