Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600676 | 0.92 | PPARG (0.44) | PPARGALDH1A1LMNA | |
| SCHEMBL4600790 | 0.87 | PPARG (0.40) | PPARGALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL27737138 | 0.85 | PPARG (0.44) | PPARGALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL4602019 | 0.84 | PPARG (0.45) | PPARGALDH1A1HTTDUTKMT2A | |
| SCHEMBL4601397 | 0.83 | PPARG (0.41) | PPARGDUT | |
| SCHEMBL4634146 | 0.82 | PPARG (0.46) | PPARGDUT | |
| SCHEMBL4602137 | 0.81 | PPARG (0.41) | PPARGPOLB | |
| SCHEMBL4602607 | 0.79 | PPARG (0.43) | PPARG | |
| SCHEMBL4601653 | 0.77 | PPARG (0.71) | PPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27737206 | 0.75 | PPARG (0.41) | PPARGALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |