Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232306 | 0.83 | ALDH1A1 (0.40) | PDK1PDK2PDK3PDK4TSHR | |
| SCHEMBL13617971 | 0.81 | KCNN4 (0.45) | KCNN4PDK1PDK2PDK3PDK4 | |
| SCHEMBL803006 | 0.81 | KCNN4 (0.45) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL17109738 | 0.77 | KCNN4 (0.42) | KCNN4PDK1PDK2PDK3PDK4 | |
| SCHEMBL3671355 | 0.76 | KCNN4 (0.45) | KCNN4PDK1PDK2PDK3PDK4 | |
| SCHEMBL7571745 | 0.75 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL5966718 | 0.75 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL78489 | 0.75 | TSHR (0.50) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL809831 | 0.75 | KCNN4 (0.48) | KCNN4PDK2TSHRLMNAHSD11B1 | |
| SCHEMBL29467226 | 0.75 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489064-B1 | Preparation of fluorinated acetophenones | SALTIGO GMBH (DE) | 2008-04-16 | — | — | EP | disclosed |
| US-7148384-B2 | Preparation of fluorinated acetophenones | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20050043559-A1 | Preparation of fluorinated acetophenones | LANXESS DEUTSCHLAND GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1489064-A1 | Preparation of fluorinated acetophenones | Bayer Chemicals AG (DE) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043559-A1 | Preparation of fluorinated acetophenones | GNPAT, HNF4A, FAH | KCNN4 3760/4885PDK1 2033/4885PDK2 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.