Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17109738 | 0.81 | KCNN4 (0.42) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL4601609 | 0.81 | KCNN4 (0.42) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL21497368 | 0.81 | ALDH1A1 (0.43) | TSHRLMNAHSD11B1HTR2CALDH1A1 | |
| SCHEMBL7571745 | 0.79 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL5966718 | 0.79 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL15998876 | 0.79 | ALDH1A1 (0.43) | TSHRLMNAHSD11B1HTR2CALDH1A1 | |
| SCHEMBL78489 | 0.79 | TSHR (0.50) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL809831 | 0.79 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL29467226 | 0.79 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 | |
| SCHEMBL117692 | 0.79 | KCNN4 (0.48) | KCNN4TSHRLMNAHSD11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790858-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | Glucox Biotech AB (SE) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215291-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2019-11-14 | — | — | WO | disclosed |
| US-20150266856-A1 | RORGamma Modulators | EXELIXIS, INC. | 2015-09-24 | — | — | US | disclosed |
| EP-1499311-B1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2009-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266856-A1 | RORGamma Modulators | RORB, RORA, RORC | KCNN4 2530/4885TSHR 227/4885LMNA 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.