Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648348 | 0.79 | SIGMAR1 (0.60) | KCNA3AKT1NSD2DRD2KMT2A | |
| SCHEMBL14223071 | 0.78 | ALOX15 (0.49) | KCNA3AKT1NSD2DRD2CKS1B | |
| SCHEMBL1956790 | 0.78 | CYP3A4 (0.49) | KCNA3AKT1NSD2DRD2CKS1B | |
| SCHEMBL7078816 | 0.78 | DRD4 (0.58) | KCNA3AKT1DRD2DRD3CKS1B | |
| SCHEMBL2731871 | 0.78 | GPR119 (0.45) | NSD2CKS1BSKP1SKP2KMT2A | |
| SCHEMBL26640819 | 0.77 | KCNA3 (0.50) | KCNA3AKT1NSD2DRD2DRD3 | |
| SCHEMBL1956090 | 0.76 | KCNA3 (0.47) | KCNA3AKT1NSD2DRD2DRD3 | |
| SCHEMBL915402 | 0.76 | KMT2A (0.65) | KCNA3DRD2DRD3KMT2AL3MBTL1 | |
| SCHEMBL24247901 | 0.75 | KCNA3 (0.46) | KCNA3AKT1NSD2DRD2CKS1B | |
| SCHEMBL16854336 | 0.75 | ALDH1A1 (0.55) | KCNA3AKT1DRD2DRD3CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914235-A1 | CHIRAL TETRA-HYDRO BETA-CARBOLINE DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | Universite de Lille 2 Droit et Santé (FR) | 2008-04-23 | — | — | EP | disclosed |
| EP-1914235-A1 | CHIRAL TETRA-HYDRO BETA-CARBOLINE DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | Universite de Lille 2 Droit et Santé (FR) | 2008-04-23 | — | — | EP | disclosed |