Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL460210

CCn1cc[n+](C)c1.CCn1cc[n+](C)c1.O=C([O-])C(F)(F)F.O=S(=O)([N-]S(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372352 0.91 SMN1; SMN2 (0.38) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL29434929 0.91 SMN1; SMN2 (0.38) FDPSSMN1; SMN2LMNAMEN1APAF1
Lithium SCHEMBL29973484 0.89 SMN1; SMN2 (0.37) FDPSSMN1; SMN2LMNAMEN1APAF1
Trifluoroacetic Acid SCHEMBL358902 0.88 FDPS (0.43) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL8080635 0.82 SMN1; SMN2 (0.36) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL29472316 0.80 SMN1; SMN2 (0.40) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL29395782 0.80 SMN1; SMN2 (0.46) FDPSSMN1; SMN2LMNAMEN1APAF1
Trifluoromethanesulfonic Acid SCHEMBL133213 0.79 FDPS (0.40) FDPSSMN1; SMN2LMNAMEN1APAF1
Trifluoromethanesulfonic Acid SCHEMBL27688882 0.79 FDPS (0.40) FDPSSMN1; SMN2LMNAMEN1APAF1
SCHEMBL3678674 0.79 SMN1; SMN2 (0.39) FDPSSMN1; SMN2LMNAMEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102650-B1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AGENCY SCIENCE TECH & RES (SG) 2021-05-19 EP disclosed
US-10458979-B2 Solid supported artificial cell membrane system AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-10-29 US disclosed
US-10364350-B2 Vesicular system and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-07-30 US disclosed
US-10350172-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-07-16 US disclosed
EP-2890719-B1 SOLID SUPPORTED ARTIFICIAL CELL MEMBRANE SYSTEM AGENCY SCIENCE TECH & RES (SG) 2019-04-17 EP disclosed
US-20190046455-A1 STIMULI-RESPONSIVE INTERPOLYMER COMPLEX COATED HOLLOW SILICA VESICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-02-14 US disclosed
US-10022332-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-07-17 US disclosed
US-9887316-B2 Quantum dots, method, and devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-06 US disclosed
EP-2791327-B1 FOAM ADSORPTION AMLIKA MERCANTILE PRIVATE LTD (AMPL) (IN) 2017-08-30 EP disclosed
US-9416009-B2 Method for modifying electrical properties of carbon nanotubes NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-08-16 US disclosed
US-20100298504-A1 AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-25 US disclosed
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-11-25 US disclosed
US-20100285573-A1 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-11 US disclosed
WO-2010123462-A1 VESICULAR SYSTEM AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-10-28 WO disclosed
US-20100228058-A1 CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-09-09 US disclosed
US-20090289213-A1 METHOD OF PROCESSING A BIOLOGICAL AND/OR CHEMICAL SAMPLE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-11-26 US disclosed
US-20090239338-A1 Method of Forming an Interconnect on a Semiconductor Substrate NANYANG TECHNOLOGICAL UNIVERSITY 2009-09-24 US disclosed
EP-2102650-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME Agency for Science, Technology And Research (SG) 2009-09-23 EP disclosed
US-20090023127-A1 TISSUE SYSTEM AND METHODS OF USE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-01-22 US disclosed
WO-2008063136-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100228058-A1 CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND DHPS, GGPS1, COASY FDPS 4/4885SMN1; SMN2 4406/4885LMNA 2075/4885
US-10350172-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles CD44, NSF, SUMO3 FDPS 750/4885SMN1; SMN2 4701/4885LMNA 4244/4885
US-10022332-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles CD44, NSF, SUMO3 FDPS 750/4885SMN1; SMN2 4701/4885LMNA 4244/4885
US-20190046455-A1 STIMULI-RESPONSIVE INTERPOLYMER COMPLEX COATED HOLLOW SILICA VESICLES CD44, NSF, SUMO3 FDPS 750/4885SMN1; SMN2 4701/4885LMNA 4244/4885
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NQO1, COASY, NOS2 FDPS 96/4885SMN1; SMN2 1412/4885LMNA 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.