SCHEMBL4602393

SCHEMBL4602393

CCCCCCN1CCCN(c2ccccc2)C1=O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.52
DRD3 P35462 1/20 0.52
S1PR1 P21453 1/20 0.51
CYP1A1 P04798 6/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
GRM2 Q14416 4/20 0.45
PER2 O15055 1/20 0.45
CNR2 P34972 3/20 0.43
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686095 0.91 S1PR1 (0.60) DRD2DRD3S1PR1CYP1A1MEN1
SCHEMBL12013778 0.80 ALDH1A1 (0.51) DRD2DRD3S1PR1CYP1A1
SCHEMBL17836960 0.79 ALOX5 (0.47) S1PR1CNR2CNR1
SCHEMBL7337557 0.79 DRD2 (0.57) DRD2DRD3MEN1NPC1RAB9A
SCHEMBL14698020 0.79 DRD2 (0.65) DRD2DRD3S1PR1CYP1A1MEN1
SCHEMBL4602079 0.78 ALOX5 (0.46) S1PR1MEN1KMT2A
SCHEMBL14917572 0.78 ALOX5 (0.44) S1PR1CYP1A1MEN1KMT2A
SCHEMBL9782004 0.75 EEF2K (0.43)
SCHEMBL27677921 0.75 ALOX5 (0.44) S1PR1PER2CNR2
SCHEMBL6561542 0.75 ALOX5 (0.44) S1PR1PER2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100441614-C Method for modifying fluoropolymer matrix and composite article thereof 3M INNOVATIVE PROPERTIES CO (US) 2008-12-10 CN disclosed
EP-1694748-B1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES CO (US) 2008-04-23 EP disclosed
US-7273531-B2 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-25 US disclosed
CN-1878825-A Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES CO (US) 2006-12-13 CN disclosed
EP-1694748-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M Innovative Properties Company (US) 2006-08-30 EP disclosed
WO-2005047373-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-26 WO disclosed
US-20050092429-A1 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY 2005-05-05 US disclosed