Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781753 | 0.91 | EEF2K (0.42) | EEF2KKCNH2FKBP1AALDH1A1CETP | |
| SCHEMBL19055901 | 0.84 | ALDH1A1 (0.45) | ALDH1A1PREP | |
| SCHEMBL18655950 | 0.76 | ALDH1A1 (0.47) | ALDH1A1PREP | |
| SCHEMBL4602393 | 0.75 | DRD2 (0.52) | — | |
| SCHEMBL17836960 | 0.74 | ALOX5 (0.47) | ALDH1A1 | |
| SCHEMBL2084509 | 0.74 | ALDH1A1 (0.39) | KCNH2ALDH1A1 | |
| SCHEMBL4602079 | 0.73 | ALOX5 (0.46) | ALDH1A1 | |
| SCHEMBL14917572 | 0.72 | ALOX5 (0.44) | ALDH1A1 | |
| SCHEMBL6561542 | 0.70 | ALOX5 (0.44) | ALDH1A1 | |
| SCHEMBL27677921 | 0.70 | ALOX5 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066658-A | Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |