Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309448 | 0.83 | KMT2A (0.56) | ALDH1A1SMN1; SMN2LMNAKMT2AL3MBTL1 | |
| SCHEMBL4603068 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL28424009 | 0.81 | L3MBTL1 (0.47) | ALDH1A1SMN1; SMN2KDM4ELMNAL3MBTL1 | |
| SCHEMBL4602273 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL21245560 | 0.78 | CDK1 (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL15687836 | 0.78 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL4602884 | 0.77 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL14577881 | 0.76 | HTR1A (0.57) | ALDH1A1SMN1; SMN2KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8934418 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| Hydrochloric Acid SCHEMBL7242189 | 0.76 | HTR1A (0.56) | ALDH1A1SMN1; SMN2KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |