Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72463 | 0.85 | MEN1 (0.36) | — | |
| SCHEMBL14166663 | 0.84 | HSP90AA1 (0.48) | FAAH | |
| SCHEMBL4732400 | 0.84 | HSP90AA1 (0.53) | FAAHCES2CES1 | |
| SCHEMBL4732709 | 0.84 | HSP90AA1 (0.53) | FAAHCES2CES1 | |
| SCHEMBL4731984 | 0.84 | HSP90AA1 (0.53) | FAAHCES2CES1 | |
| SCHEMBL8091952 | 0.83 | FAAH (0.43) | FAAHPTPN1CES2 | |
| SCHEMBL26244153 | 0.82 | APP (0.41) | — | |
| SCHEMBL3220018 | 0.81 | PTPN1 (0.43) | FAAHPTPN1CES2 | |
| SCHEMBL13113281 | 0.81 | FAAH (0.41) | FAAHPTPN1CES2CES1 | |
| SCHEMBL8292803 | 0.80 | HSP90AA1 (0.53) | FAAHPTPN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |