Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601014 | 0.89 | GPR84 (0.42) | PPARGROS1ALKGPR84NPC1 | |
| SCHEMBL4602109 | 0.89 | GPR84 (0.43) | PPARGROS1ALKGPR84NPC1 | |
| SCHEMBL4600676 | 0.88 | PPARG (0.44) | PPARGNPC1RAB9ATDP1 | |
| SCHEMBL4600593 | 0.86 | PPARG (0.43) | PPARGROS1ALKGPR84POLB | |
| SCHEMBL4602607 | 0.84 | PPARG (0.43) | PPARGGRM5NPC1RAB9A | |
| SCHEMBL27737206 | 0.81 | PPARG (0.41) | PPARGROS1ALKGPR84GRM5 | |
| SCHEMBL4602971 | 0.81 | PPARG (0.41) | PPARGPOLB | |
| SCHEMBL4602019 | 0.77 | PPARG (0.45) | PPARGTDP1 | |
| SCHEMBL4600790 | 0.77 | PPARG (0.40) | PPARGPOLB | |
| SCHEMBL4600582 | 0.76 | PPARG (0.60) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |