Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649846 | 0.82 | HDAC4 (0.48) | HDAC4CTNNB1WNT3ANOTUMCFTR | |
| SCHEMBL12038 | 0.70 | GPR3 (0.33) | — | |
| SCHEMBL19492664 | 0.65 | HDAC4 (0.43) | HDAC4CTNNB1WNT3ANOTUMCFTR | |
| SCHEMBL29575189 | 0.65 | HDAC4 (0.48) | HDAC4CTNNB1WNT3ANOTUMCFTR | |
| SCHEMBL18828501 | 0.65 | HDAC4 (0.48) | HDAC4CTNNB1WNT3ANOTUMCFTR | |
| SCHEMBL7533426 | 0.64 | — | — | |
| SCHEMBL7538766 | 0.64 | — | — | |
| SCHEMBL200514 | 0.62 | GPR3 (0.45) | HDAC4CTNNB1WNT3ANOTUM | |
| SCHEMBL22347139 | 0.61 | HDAC4 (0.42) | HDAC4CTNNB1WNT3ANOTUMCFTR | |
| SCHEMBL23995206 | 0.61 | HDAC4 (0.42) | HDAC4CTNNB1WNT3ANOTUMCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753512-B1 | TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | claimed |