SCHEMBL12038

SCHEMBL12038

FC1(F)Oc2[c]cccc2O1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3530761 0.83
SCHEMBL793316 0.75 TSHR (0.41)
SCHEMBL7533426 0.72
SCHEMBL200514 0.71 GPR3 (0.45) GPR3
SCHEMBL2469503 0.71
SCHEMBL9588618 0.71
SCHEMBL4603091 0.70 HDAC4 (0.41)
SCHEMBL3292005 0.67
SCHEMBL351335 0.67 NOTUM (0.32)
SCHEMBL351151 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128305-A1 2-AZABICYCLO[3.1.1]HEPTANE COMPOUND 第一三共株式会社 2024-06-20 WO claimed
CN-118201911-A Compounds and their use as GPR183 inhibitors 南京艾美斐生物医药科技有限公司 2024-06-14 CN claimed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US claimed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
EP-3741757-B1 DIHYDROINDOLIZINONE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2023-07-26 EP claimed
US-11530211-B2 Dihydroindolizinone derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-12-20 US claimed
CN-109923116-B [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as PDE2 inhibitors 詹森药业有限公司 2022-12-06 CN claimed
EP-3998107-A1 METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES Tokyo Institute of Technology (JP) 2022-05-18 EP claimed
EP-3957636-A1 FUNGICIDAL OXADIAZOLES FMC Corporation (US) 2022-02-23 EP claimed
CN-114040966-A Method for producing insulin-producing cell using dihydroindolizinone derivative 国立大学法人东京工业大学 2022-02-11 CN claimed
WO-1998043480-A1 FUNGICIDE COMPOSITIONS CONTAINING A 3-PHENYL-PYRAZOLE RHONE-POULENC AGRO (FR) 1998-10-08 WO claimed
US-5536725-A Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines FMC CORPORATION (US) 1996-07-16 US claimed
EP-0505742-A2 Process for the production of 4-cyanopyrrole compounds substituted at the 3-position BAYER AG (DE) 1992-09-30 EP claimed
US-4897416-A 5-OXIMINO-13B-CARBONYLTHIOMILBEMYCIN DERIVATIVES CIBA-GEIGY CORPORATION (US) 1990-01-30 US claimed
EP-0097425-B1 FUNGICIDAL OR PLANT GROWTH REGULATING TRIAZOLYL ETHANOLS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-08 EP claimed
EP-0048548-B1 PHARMACEUTICAL COMPOSITIONS OF FUNGICIDAL TRIAZOLE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP claimed
EP-0097425-A2 Fungicidal or plant growth regulating triazolyl ethanols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-04 EP claimed
US-4344960-A Combating insects and acarids with 3-(2-chloro-3,3,4,4,4-pentafluoro-1-butenyl)-2,2-dimethyl-cyclopropanecarboxylic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1982-08-17 US claimed
EP-0048548-A1 Pharmaceutical compositions of fungicidal triazole derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-31 EP claimed
EP-0040742-A1 3-(Chloro-3,3,4,4,4-pentafluoro-1-butenyl)-2,2-dimethylcyclopropanecarboxylic acid esters, process for their preparation and their use in insecticides BAYER AG (DE) 1981-12-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF MPO, SSB, SGMS2 GPR3 3949/4885
US-11530211-B2 Dihydroindolizinone derivative INSR, GPR119, IAPP GPR3 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.