Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602884 | 0.90 | L3MBTL1 (0.52) | BLML3MBTL1ALDH1A1LMNATDP1 | |
| SCHEMBL4604364 | 0.82 | KDM4E (0.50) | ALDH1A1TDP1HTTSMN1; SMN2KDM4E | |
| SCHEMBL4605773 | 0.80 | LMNA (0.52) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL5525074 | 0.76 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1MAPTTDP1HTT | |
| SCHEMBL3114233 | 0.75 | SMN1; SMN2 (0.56) | ALDH1A1LMNAMAPTTDP1SMN1; SMN2 | |
| SCHEMBL25397720 | 0.75 | MAPT (0.48) | BLML3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL31681808 | 0.75 | MAPT (0.48) | BLML3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL571956 | 0.75 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1MAPTTDP1HTT | |
| SCHEMBL29710198 | 0.73 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTTDP1HTT | |
| SCHEMBL6609562 | 0.73 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |