Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350547 | 0.98 | CA12 (0.39) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL17363295 | 0.89 | CA12 (0.39) | CA12CA1CA9ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL7773830 | 0.85 | CA12 (0.32) | CA12CA1CA9ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL1535756 | 0.78 | CA12 (0.40) | CA12CA1CA9ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL31303166 | 0.78 | MGLL (0.36) | CA12CA1CA9ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL6265698 | 0.77 | CA12 (0.39) | CA12CA1CA9ALDH1A1ALDH2 | |
| SCHEMBL1713038 | 0.76 | CA12 (0.41) | CA12CA1CA9ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL25406366 | 0.75 | CA12 (0.38) | CA12CA1CA9ALDH1A1ALDH2 | |
| Fluoride Ion SCHEMBL5446663 | 0.74 | CA12 (0.40) | CA12CA1CA9ALDH1A1ALDH2 | |
| Bromide SCHEMBL6155069 | 0.74 | CA12 (0.40) | CA12CA1CA9ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895991-B1 | Halogenating agent | MITSUI CHEMICALS INC (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-6632949-B2 | Difluoro-diamine methylene derivatives | MITSUI CHEMICALS, INC. (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20030004348-A1 | Halogenating agents | SONODA HIROSHI (JP) | 2003-01-02 | — | — | US | disclosed |
| US-6458990-B1 | BIS(DIHYDROCARBYLAMINO)DIFLUOROMETHANE OR CYCLIC DERIVATIVES THEREOF; FORMING BY REACTING ALKALI METAL HALIDE WITH THE CORRESPONDING AMIDINIUM SALT; FLUORINATION OF ALCOHOLS, THIOPHENOLS, ALDEHYDES, AND KETONES | MITSUI CHEMICALS, INC. (JP) | 2002-10-01 | — | — | US | disclosed |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | SONODA HIROSHI (JP) | 2002-04-11 | — | — | US | disclosed |
| US-6329529-B1 | FOR FLUORINATING OF ORGANIC COMPOUNDS, EFFICIENCY, POLLUTION CONTROL | MITSUI CHEMICALS, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1073088-C | method for preparing organic disulphides and polysulphides in the presence of polystyrene-divinylbenzene (PS-DVB) resins containing guanidine and amidine groups | ELF AQUITAINE (FR) | 2001-10-17 | — | — | CN | disclosed |
| EP-0769512-B1 | Process for preparing polycondensation polymers using haloiminium salts as condensation agents | MITSUI CHEMICALS INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-5973080-A | MODIFIED DIVINYLBENZENE-STYRENE COPOLYMER | ELF AQUITAINE PRODUCTION (FR) | 1999-10-26 | — | — | US | disclosed |
| EP-0895991-A2 | Halogenating agent | Mitsui Chemicals, Inc. (JP) | 1999-02-10 | — | — | EP | disclosed |
| CN-1204317-A | Method for preparing organic disulphides and polysulphides in presence of polystyrene-divinylbenzene (PS-DVB) resins having guanidine or amidine groups | ELF AQUITAINE (FR) | 1999-01-06 | — | — | CN | disclosed |
| US-5817716-A | MODIFIED DIVINYLBENZENE-STYRENE COPOLYMER | ELF AQUITAINE PRODUCTION (FR) | 1998-10-06 | — | — | US | disclosed |
| US-5767229-A | REACTING SULFUR WITH MERCAPTAN OR LOWER ORDER POLYSULFIDE TO FORM DISULFIDE OR HIGHER ORDER POLYSULFIDE | ELF AQUITAINE PRODUCTION (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5726253-A | REACTING DIVINYLBENZENE-STYRENE RESIN WITH CHLOROFORMAMIDINIUM CHLORIDE IN BASE | ELF AQUITAINE PRODUCTION (FR) | 1998-03-10 | — | — | US | disclosed |
| US-5719256-A | CONDENSING CARBOXYL GROUP CONTAINING COMPOUND AND ACTIVE HYDROGEN CONTAINING COMPOUND IN PRESENCE OF HALOIMINIUM SALT AS POLYMERIZATION CATALYST | MITSU TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0769512-A2 | Process for preparing polycondensation polymers | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-4806286-A | CATALYSIS WITH GUANIDINIUM SALT; PESTICIDES, POLYMERIZATION CATALYSTS | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004348-A1 | Halogenating agents | AFF1, NAF1, AFF2 | CA12 2840/4885CA1 1826/4885CA9 1766/4885 |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | AFF1, NAF1, CYP2F1 | CA12 3080/4885CA1 1663/4885CA9 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.