Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 7/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382573 | 0.90 | ITGB3 (0.43) | ITGB3ITGA2BITGAVKCNH2SFRP1 | |
| SCHEMBL383161 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BITGAVSFRP1CASR | |
| SCHEMBL460323 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BITGAVKCNH2SFRP1 | |
| SCHEMBL382384 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BITGAV | |
| SCHEMBL7655429 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BITGAVKCNH2SFRP1 | |
| SCHEMBL383585 | 0.80 | ITGB3 (0.64) | ITGB3ITGA2BITGAVSFRP1CTSL | |
| SCHEMBL382383 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BITGAVKCNH2SFRP1 | |
| SCHEMBL460322 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BITGAVKCNH2CASR | |
| SCHEMBL382447 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BITGAVSFRP1CASR | |
| SCHEMBL6499277 | 0.78 | SFRP1 (0.41) | ITGB3ITGA2BITGAVSFRP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |