Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SENP5 | Q96HI0 | 3/20 | 0.47 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604994 | 0.91 | PTPN1 (0.53) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL4603300 | 0.90 | PTPN2 (0.51) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL4604564 | 0.89 | SENP2 (0.59) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL11844857 | 0.87 | PTPN1 (0.76) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL8618124 | 0.86 | ALDH1A1 (0.59) | KMT2AALDH1A1LMNASENP5SENP2 | |
| SCHEMBL4605385 | 0.85 | CXCR2 (0.48) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL4605404 | 0.85 | PPARA (0.48) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL4604537 | 0.84 | SENP2 (0.60) | ALDH1A1SENP5SENP2SENP1 | |
| SCHEMBL4605718 | 0.84 | PTPN1 (0.46) | PTPN1PTPN2KMT2AALDH1A1LMNA | |
| SCHEMBL4604056 | 0.84 | PTPN1 (0.60) | PTPN1PTPN2KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685122-B1 | BENZOFURANS AND BENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-7371774-B2 | Benzofurans and benzothiophenes | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20070066680-A1 | Benzofurans and benzothiophenes | MERCK PATENT GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066680-A1 | Benzofurans and benzothiophenes | INSR, GPR119, IGF1R | PTPN1 2031/4885PTPN2 2576/4885KMT2A 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.