Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603593 | 1.00 | ALOX5 (0.50) | ALOX5MEN1KMT2APIM1RAB9A | |
| SCHEMBL2995792 | 0.86 | DYRK3 (0.39) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2995795 | 0.86 | DYRK3 (0.39) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2996292 | 0.85 | ALOX5 (0.40) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2987520 | 0.85 | F11 (0.39) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2788265 | 0.85 | ACHE (0.41) | ALOX5MEN1KMT2ACISD1 | |
| SCHEMBL2996287 | 0.85 | ALOX5 (0.40) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2987521 | 0.85 | F11 (0.39) | ALOX5MEN1KMT2APIM1CISD1 | |
| SCHEMBL2788267 | 0.85 | ACHE (0.41) | ALOX5MEN1KMT2ACISD1 | |
| SCHEMBL2993913 | 0.84 | CISD1 (0.39) | ALOX5MEN1KMT2APIM1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2008-10-23 | — | — | US | disclosed |
| EP-1940812-A2 | NOVEL CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007038331-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | ALOX5 4177/4885MEN1 4161/4885KMT2A 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.