Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | SENP5 | Q96HI0 | 2/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605156 | 0.88 | KMT2A (0.47) | PTPN1KMT2AF2MAPTPPARG | |
| SCHEMBL4633529 | 0.87 | PTPN1 (0.50) | PTPN1KMT2AF2MAPTPPARG | |
| SCHEMBL4606731 | 0.87 | PTPN1 (0.52) | PTPN1KMT2APPARGPPARAEDNRA | |
| SCHEMBL4605028 | 0.85 | KMT2A (0.49) | PTPN1KMT2AF2MAPTPPARG | |
| SCHEMBL4607131 | 0.83 | KMT2A (0.47) | PTPN1KMT2AF2MAPTEDNRA | |
| SCHEMBL4605133 | 0.78 | ALDH1A1 (0.51) | PTPN1KMT2AMAPTEDNRASENP5 | |
| SCHEMBL4605351 | 0.76 | ALDH1A1 (0.48) | PTPN1KMT2APPARGPPARASENP5 | |
| SCHEMBL4633994 | 0.75 | PPARG (0.44) | PTPN1KMT2AMAPTPPARGPPARA | |
| SCHEMBL4606177 | 0.75 | PPARG (0.44) | PTPN1KMT2AMAPTPPARGPPARA | |
| SCHEMBL4604720 | 0.73 | LMNA (0.50) | PTPN1KMT2AMAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685122-B1 | BENZOFURANS AND BENZOTHIOPHENES | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-7371774-B2 | Benzofurans and benzothiophenes | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20070066680-A1 | Benzofurans and benzothiophenes | MERCK PATENT GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066680-A1 | Benzofurans and benzothiophenes | INSR, GPR119, IGF1R | PTPN1 2031/4885KMT2A 2846/4885F2 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.