Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602882 | 0.98 | CNR1 (0.44) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4603116 | 0.95 | ALDH1A1 (0.42) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4602587 | 0.87 | HPGD (0.42) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4603506 | 0.84 | HPGD (0.45) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4603249 | 0.82 | HTR2A (0.41) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4604028 | 0.81 | ALDH1A1 (0.48) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4605222 | 0.79 | HPGD (0.41) | CNR1CNR2ALDH1A1RAB9AHTR2A | |
| SCHEMBL4604866 | 0.78 | ALDH1A1 (0.51) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4604804 | 0.78 | HTR2A (0.35) | ALDH1A1HTR2A | |
| SCHEMBL4604443 | 0.77 | TAS1R3 (0.50) | CNR1CNR2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |