Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500407 | 0.86 | SMN1; SMN2 (0.40) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL12264169 | 0.81 | MEN1 (0.53) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL490866 | 0.80 | CES1 (0.47) | KMT2AMAPTPOLBTSHRCES1 | |
| SCHEMBL7207416 | 0.79 | PIN1 (0.49) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7212419 | 0.77 | PIN1 (0.46) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28210809 | 0.77 | MEN1 (0.49) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7212428 | 0.77 | PIN1 (0.46) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL28101975 | 0.75 | EDNRB (0.46) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL15991494 | 0.75 | EDNRB (0.46) | PIN1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7207418 | 0.74 | PIN1 (0.44) | PIN1MEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871339-A1 | UV PROTECTION | Merck Patent GmbH (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111234-A1 | UV PROTECTION | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |