Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604804 | 0.81 | HTR2A (0.35) | P2RX7 | |
| SCHEMBL4604866 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2A | |
| SCHEMBL4604028 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2A | |
| SCHEMBL4601677 | 0.78 | P2RX7 (0.35) | P2RX7TP53 | |
| SCHEMBL4602866 | 0.78 | NR4A1 (0.34) | P2RX7TP53KMT2A | |
| SCHEMBL3797362 | 0.75 | NR4A1 (0.32) | KMT2A | |
| SCHEMBL4248415 | 0.72 | TP53 (0.53) | P2RX7TP53SLC6A5 | |
| SCHEMBL12850756 | 0.71 | TP53 (0.52) | TP53SLC6A5MEN1KMT2AHTT | |
| SCHEMBL4244663 | 0.70 | TP53 (0.58) | P2RX7TP53SLC6A5 | |
| SCHEMBL4604665 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |