Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604804 | 0.86 | HTR2A (0.35) | P2RX7HTR2ACYP2B6 | |
| SCHEMBL4603987 | 0.78 | P2RX7 (0.38) | P2RX7TP53 | |
| SCHEMBL4603150 | 0.75 | TAS1R3 (0.51) | SMN1; SMN2 | |
| SCHEMBL4604443 | 0.74 | TAS1R3 (0.50) | CNR2 | |
| SCHEMBL4604851 | 0.73 | HTR2A (0.34) | P2RX7HTR2ACYP2B6 | |
| SCHEMBL4604638 | 0.67 | ALDH1A1 (0.46) | CNR2 | |
| SCHEMBL4605222 | 0.66 | HPGD (0.41) | HTR2ACNR2 | |
| SCHEMBL4245123 | 0.66 | SLC6A5 (0.58) | P2RX7CYP2B6LMNASMN1; SMN2TP53 | |
| SCHEMBL4602808 | 0.66 | HPGD (0.44) | CNR2 | |
| SCHEMBL4604358 | 0.65 | TAS1R3 (0.41) | HTR2APDE4BCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |