Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797362 | 0.86 | NR4A1 (0.32) | NR4A1NR4A2DHODHKMT2A | |
| SCHEMBL4244884 | 0.83 | CTSK (0.40) | NR4A1NR4A2DHODHANO1CNR2 | |
| SCHEMBL4603970 | 0.79 | SCN9A (0.33) | SCN9AKAT6A | |
| SCHEMBL4603987 | 0.78 | P2RX7 (0.38) | TP53KMT2AP2RX7 | |
| SCHEMBL4618468 | 0.76 | KAT6A (0.35) | NR4A1NR4A2DHODHKAT6AKMT2A | |
| SCHEMBL4603743 | 0.75 | TAS1R3 (0.46) | — | |
| SCHEMBL4248762 | 0.74 | CTSK (0.44) | ANO1CNR2CTSLCTSSCTSK | |
| SCHEMBL12850756 | 0.73 | TP53 (0.52) | TP53KMT2AP2RX3 | |
| SCHEMBL2296086 | 0.73 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL4249769 | 0.73 | TP53 (0.43) | CTSLCTSSCTSKTP53P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |