SCHEMBL460421

SCHEMBL460421

O=C(O)c1ccc(C(=O)O)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.55
KDM4E B2RXH2 3/20 0.52
TSHR P16473 3/20 0.48
TP53 P04637 1/20 0.48
MYC P01106 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
PTGS2 P35354 1/20 0.46
CA7 P43166 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4957114 0.98 LMNA (0.53) LMNAMAPK1HTTRAB9AKDM4E
Hydrochloric Acid SCHEMBL26689957 0.98 LMNA (0.53) LMNAMAPK1HTTRAB9AKDM4E
SCHEMBL2822484 0.89 KDM4E (0.51) LMNAMAPK1HTTRAB9AKDM4E
SCHEMBL19331714 0.85 RAB9A (0.55) LMNAMAPK1HTTRAB9AKDM4E
SCHEMBL2529523 0.85 DGAT1 (0.58) LMNAMAPK1HTTRAB9AKDM4E
SCHEMBL392941 0.85 DGAT1 (0.48) LMNAMAPK1HTTRAB9ATSHR
SCHEMBL1951639 0.85 AKR1C3 (0.51) LMNAMAPK1HTTRAB9AEPHX2
SCHEMBL4825443 0.84 LMNA (0.49) LMNAMAPK1HTTRAB9AKDM4E
SCHEMBL16534012 0.84 KDM4E (0.68) LMNAKDM4ETSHRTP53HSD17B10
SCHEMBL13544505 0.82 SORT1 (0.45) LMNAMAPK1HTTRAB9AMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120119314-A Expandable preparation method of ultrathin two-dimensional MOF/GO/MOF sandwich-like single-crystal nano-sheet 中国石油大学(华东) 2025-06-10 CN claimed
CN-119588326-B Preparation method of ferroferric oxide@fluorine-containing organic framework core-shell structure material for water-oil separation 济南大学 2025-06-10 CN claimed
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
CN-116162254-B Preparation method and application of metal organic framework material 中国科学院上海应用物理研究所 2025-04-29 CN claimed
CN-119838432-A Suitable for low-concentration CO2Preparation method and application of separated membrane material 天津工业大学 2025-04-18 CN claimed
CN-119800439-A Bimetallic oxygen evolution pre-catalyst material based on metal organic framework, and preparation method and application thereof 浙江工业大学 2025-04-11 CN claimed
CN-119733393-A MIL-101-F-based mixed matrix membrane preparation method and application 北京工业大学 2025-04-01 CN claimed
CN-119588326-A Preparation method of ferroferric oxide@fluorine-containing organic framework core-shell structure material 济南大学 2025-03-11 CN claimed
CN-119529310-A Metal organic framework nano material with adjustable photo-thermal performance and preparation method thereof 浙江工业大学 2025-02-28 CN claimed
CN-119524926-A Preparation method of small-size defect cerium-based MOFs supported metal catalyst for hydrogenation 北京科技大学 2025-02-28 CN claimed
EP-1527493-B1 PROTON-CONDUCTING POLYMER MEMBRANE COMPRISING A POLYMER WITH PHOSPHONIC ACID GROUPS AND USE THEREOF IN FUEL CELLS PEMEAS GMBH (DE) 2006-01-04 EP claimed
EP-1527494-B1 PROTON-CONDUCTING POLYMER MEMBRANE COMPRISING A POLYMER WITH SULPHONIC ACID GROUPS AND USE THEREOF IN FUEL CELLS PEMEAS GMBH (DE) 2005-12-28 EP claimed
US-20050256296-A1 Polymer film based on polyazoles, and uses thereof BASF FUEL CELL GMBH (DE) 2005-11-17 US claimed
US-20050244694-A1 Proton-conducting polymer membrane comprising polymers containing phosphonic acid groups and its use in fuel cells PEMEAS GMBH (DE) 2005-11-03 US claimed
US-20050244695-A1 vinyl-containing sulfonic acid polymerized in presence of one or more aromatic tetraamino compounds and with one or more aromatic carboxylic acids, their esters, their acid halides or their acid anhydrides; interpenetrating polymer network BASF FUEL CELL GMBH (DE) 2005-11-03 US claimed
US-20040127588-A1 Proton-conducting membrane and use thereof BASF FUEL CELL GMBH (DE) 2004-07-01 US claimed
US-20040096734-A1 Proton-comducting membrane and the use thereof BASF FUEL CELL GMBH (DE) 2004-05-20 US claimed
EP-0856025-B1 CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE CELANESE VENTURES GMBH (DE) 2003-01-15 EP claimed
US-6420511-B1 SEPARATION AND PURIFICATION OF POLYESTERS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-07-16 US claimed
US-5756634-A Liquid one component PU stoving enamels HUELS AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed