Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MDH1 | P40925 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666907 | 0.94 | CYP2B6 (0.60) | MAPTCYP2B6KMT2ACYP1A2CYP3A4 | |
| SCHEMBL2282278 | 0.90 | TSHR (0.55) | MAPTCYP2B6KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12799701 | 0.87 | MAOB (0.63) | CYP2B6KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2286794 | 0.87 | TSHR (0.68) | CYP2B6KMT2APDE4BTSHRMAOB | |
| SCHEMBL2286198 | 0.85 | CYP2B6 (0.54) | CYP2B6KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15595537 | 0.85 | MAPT (0.59) | MAPTKMT2ACYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL4252982 | 0.85 | TSHR (0.66) | CYP2B6KMT2APDE4BTSHRMAOB | |
| SCHEMBL14648692 | 0.85 | KDM4E (0.50) | MAPTCYP2B6KMT2ASMN1; SMN2PDE4B | |
| SCHEMBL31747453 | 0.84 | CYP2B6 (0.53) | MAPTCYP2B6KMT2ACYP1A2CYP2C19 | |
| SCHEMBL21955097 | 0.84 | MDH1 (0.46) | MAPTCYP2B6KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435066-B2 | Substituted tricyclic compounds | LUPIN LIMITED (IN) | 2025-10-07 | — | — | US | disclosed |
| CN-114746411-B | Substituted tricyclic compounds | 印度鲁宾有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20240124938-A1 | VISUAL DETECTION OF PBD INDUCED DNA CROSSLINKS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2024-04-18 | — | — | US | disclosed |
| EP-4065575-B1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LTD (IN) | 2024-01-31 | — | — | EP | disclosed |
| US-20230013778-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2023-01-19 | — | — | US | disclosed |
| US-20230013778-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2023-01-19 | — | — | US | disclosed |
| EP-4065575-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-10-05 | — | — | EP | disclosed |
| EP-4045511-A1 | VISUAL DETECTION OF PBD INDUCED DNA CROSSLINKS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2022-08-24 | — | — | EP | disclosed |
| CN-114746411-A | Substituted tricyclic compounds | 印度鲁宾有限公司 | 2022-07-12 | — | — | CN | disclosed |
| US-20220117231-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2022-04-21 | — | — | US | disclosed |
| US-9968092-B2 | Combination of novel nitrification inhibitors and biopesticides as well as combination of (thio)phosphoric acid triamides and biopesticides | BASF SE (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | BASF SE (DE) | 2017-06-29 | — | — | US | disclosed |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | BASF SE (DE) | 2017-06-29 | — | — | US | disclosed |
| US-20170036969-A1 | NITRIFICATION INHIBITORS | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| US-20170036969-A1 | NITRIFICATION INHIBITORS | BASF SE (DE) | 2017-02-09 | — | — | US | disclosed |
| WO-2015158853-A1 | NOVEL NITRIFICATION INHIBITORS | BASF SE (DE) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015081349-A2 | COMBINATION OF NOVEL NITRIFICATION INHIBITORS AND HERBICIDES AS WELL AS COMBINATION OF (THIO)PHOSPHORIC ACID TRIAMIDES AND HERBICIDES | BASF SE (DE) | 2015-06-04 | — | — | WO | disclosed |
| US-20120046461-A1 | STEROIDAL ANTI-HORMONE HYBRIDS | NORTHEASTERN UNIVERSITY (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036969-A1 | NITRIFICATION INHIBITORS | NOS1, NOS2, NOS3 | MAPT 3764/4885CYP2B6 289/4885KMT2A 1097/4885 |
| US-20230013778-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | SOS1, RSU1, KSR1 | MAPT 150/4885CYP2B6 2709/4885KMT2A 4241/4885 |
| US-20120046461-A1 | STEROIDAL ANTI-HORMONE HYBRIDS | ESRRA, ESRRB, NR5A1 | MAPT 4598/4885CYP2B6 3333/4885KMT2A 3900/4885 |
| US-20220117231-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | NMT2, NAPRT, NAMPT | MAPT 1437/4885CYP2B6 753/4885KMT2A 1433/4885 |
| US-20170181435-A1 | Combination of Novel Nitrification Inhibitors and Biopesticides as Well as Combination of (Thio)Phosphoric Acid Triamides and Biopesticides | PRXL2A, NIT2, NAT1 | MAPT 4431/4885CYP2B6 371/4885KMT2A 3605/4885 |
| US-20240124938-A1 | VISUAL DETECTION OF PBD INDUCED DNA CROSSLINKS | LIG4, PCNA, ERCC5 | MAPT 2720/4885CYP2B6 3202/4885KMT2A 1359/4885 |
| US-20170223964-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | NAT1, PRXL2A, DDAH1 | MAPT 4472/4885CYP2B6 136/4885KMT2A 2199/4885 |
| US-12435066-B2 | Substituted tricyclic compounds | SOS1, RSU1, KSR1 | MAPT 150/4885CYP2B6 2709/4885KMT2A 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.